11/12/2014 · Because both n 1 and n 2 are >0, both revenue and cost increase with an increase in company size (Figure 2 left).Figure 2 (left) shows that larger companies such as Pfizer are at the higher end of the graph, whereas smaller companies such as Alexion are at the lower, when RPF and CPF are used as metrics, the primarily biologics companies are placed higher (outlined by red .